What is the Late Stage MSS-CRC Trial Finder?
This trial finder is a one-stop place to find and learn more about high-impact clinical trials for CRC patients. The Late Stage MSS-CRC Trial Finder is a place you can search for clinical trials that are open in your geography, and for which you may be eligible. The current data are limited to MSS (microsatellite-stable) and stage IV CRC patients. The list of trials curated here is sourced from the ClinicalTrials.gov website.
I do not fit into the microsatellite-stable (MSS) or stage IV CRC categories. Where can I find trial options?
Fight CRC has partnerships with many organizations offering clinical trial finders. They can help you find trials that are right for you. To search, visit our Clinical Trials page.
How do I learn about enrolling in a clinical trial listed on the Late Stage MSS-CRC Trial Finder?
Each trial NCT# record hyperlink has information including contact information for that trial. If the trial is at your medical center, your oncologist will likely help facilitate the process. If it is at a different medical center (often the case), you can self-refer by calling or emailing the contact information given. This does not need to be done by your doctor. Once you establish contact, the trial’s medical team will guide you through the process of what you need to do – you do not need to know this info prior to contacting them! They will tell you what appointments you need to make (and help you make them), tell you what medical records they need, and the rest of the process that is required to confirm if you are eligible for that trial.
Where is the data in CRC Trials Finder coming from and how is it curated?
All clinical trial listings on this website are sourced from ClinicalTrials.gov. The data are updated weekly. The listings are curated using a process grounded in the patient perspective, emphasizing the relationship between patient values and the desire to find clinical trials with meaningful impact for their treatment. It's important to note that this is a curated list of clinical trials (specifically for MSS-CRC), it is not comprehensive. To see the logic flow we use to sort and select the trials, view our Logic one-pager.
How many new trials are added to this resource every week?
This really depends on when data is added to the clinical trial repository at http://clinicaltrials.gov. Every week, newly added trials are curated by our team at Fight CRC and curated for inclusion in this search tool. Each week, there may be anywhere from 0-10 new CRC trials added.
Where can I find more general information about clinical trials?
This detailed Clinical Trial fact sheet has information about clinical trials that can help inform you about informed consent, eligibility, trial success and more. Additionally, visit the Fight CRC website for more information and resources on clinical trials.
What's the story behind this trial finder?
Fight CRC partnered with Dr. Tom Marsilje to expand the reach of his late-stage clinical trials tool. For two years, Tom curated a spreadsheet of clinical trials for MSS colorectal cancer patients, based on a patient viewpoint. We began working with him in January 2017 on a new-and-improved version of his spreadsheet - which has become this online tool built by Flatiron Health. Our partnership allows us to work together to expand the reach and presence of this invaluable tool for patients. This groundbreaking resource puts the patient viewpoint at the core of the clinical trials search. Tom, and all of the patients who’ve used this tool so far, have shown the power of patients and changed the game in research! For more background, read our press release.
Are Phase 1, 2 and 3 trials included in this trial finder?
Trials that are included are mostly non-Phase 1 CRC trials that only include novel (new) therapeutics and/or novel (new) techniques. This means we avoid, for example, listing phase 3 trials comparing dose schedules of drugs already commonly used to treat CRC.
How can I support this trial finder?
Powered by patients, goodwill and talent, the tool was initially built and designed during Flatiron’s “hackathon.” The Fight Colorectal Cancer research program currently hosts, updates, curates and manages the tool. Support Fight CRC research efforts.
When is a good time to start looking for trials?
Typically, oncologists will recommended clinical trials after exhausting the standard of care treatment. It’s best to begin educating yourself early about the different options and how to enroll in clinical trials, however be sure to talk to your provider to find the best time to consider a trial based on your personal health history.
Where can I find more research on IO/tumor classifications?
You can visit fightcrc.org/biomarked to learn more about biomarkers and tumor classifications.
How do I find out if my tumor is MSS or MSI-H?
Talk to your doctor if you are unsure of your tumor type. Your medical team will order the appropriate testing to determine if you are MSI-H. You can learn more at fightcrc.org/biomarked
Can I save my search options?
On the mobile app, you can save trials of interest using the “Favorites” option that resembles a star. You can also customize your searches using the filter option. On the web based tool, you can download an excel sheet of your trials to save them for later.
The information contained in this website is not intended to recommend the self management of health problems, medical conditions or wellness. It is not intended to endorse or recommend any particular type of medical treatment, physician or treatment facility. Should any reader have any health care related questions, promptly call or consult your physician or healthcare provider. The information contained in this website should NOT be used by any reader to disregard medical and/or health related advice or provide a basis to delay consultation with a physician or a qualified healthcare provider. Fight Colorectal Cancer disclaims any liability based on information provided in this website. Go here to support Fight CRC research efforts.